Subchronic Inhalation Studies of Styrene in CD Rats and CD-1 Mice
نویسندگان
چکیده
منابع مشابه
Developmental neurotoxicity study of styrene by inhalation in Crl-CD rats.
This study was conducted to assess potential adverse functional and/or morphological effects of styrene on the neurological system in the F2 offspring following F0 and F1 generation whole-body inhalation exposures. Four groups of male and female Crl:CD (SD)IGS BR rats (25/sex/group) were exposed to 0, 50, 150, and 500 ppm styrene for 6 hr daily for at least 70 consecutive days prior to mating f...
متن کاملChronic toxicity/oncogenicity study of styrene in CD rats by inhalation exposure for 104 weeks.
Groups of 70 male and 70 female Charles River CD (Sprague-Dawley-derived) rats were exposed whole body to styrene vapor at 0, 50, 200, 500, or 1000 ppm 6 h/day 5 days/week for 104 weeks. The rats were observed daily, body weights and food and water consumption were measured periodically, and a battery of hematologic and clinical pathology examinations was conducted at weeks 13, 26, 52, 78, and ...
متن کاملaccumulation of heavy metals (cu, zn, cd and pb) in sediment and selected organisms in lukut river, negrisembilan, malaysia, and toxocological studies of heavy metals (cu, zn, cd and pb) on penaeus monodon (fabricius, 1798) juveniles
چکیده ندارد.
15 صفحه اولHereditary deafness occurring in cd/1 mice.
Different strains of mice provide a valuable research tool for studying both hereditary and acquired forms of deafness. The cd/1 strain has been found to demonstrate hereditary cochlear pathology. The characteristics of hearing loss in cd/1 mice have not previously been reported. In this investigation auditory thresholds were obtained by measuring evoked brain stem responses in subjects of thre...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 1997
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/35.2.152